Health Encyclopedia

 

Health Encyclopedia Home



CryoglobulinCrioglobulina

Cryoglobulin

Does this test have other names?

Cryocrit, cryoprotein

What is this test?

This test is done to find out if you have abnormal proteins in your blood.

Blood proteins include normal immunoglobulins, or antibodies, like IgG and IgM. But they can also include antibodies linked to autoimmune diseases. These abnormal blood proteins are dissolved in your blood at body temperature, but they change into solid clumps when the blood is cooled.

These abnormal proteins are called cryoglobulins. High levels of cryoglobulins may be a sign that your body is making abnormal proteins. This condition is seen with a number of disorders and conditions, such as Raynaud's syndrome, lupus, rheumatoid arthritis, Sjogren's syndrome, leukemia, and lymphoma.

Why do I need this test?

You may need this test if your doctor suspects that you have a problem with your blood proteins. Symptoms tend to occur in cold weather and include:

  • Skin blueness

  • Numbness or tingling

  • Coldness in the fingers

In more severe cases, it can also cause joint pain or tissue damage.

What other tests might I have along with this test?

Your doctor may also order a joint fluid analysis if he or she suspects that you have a systemic inflammatory disease, such as lupus or rheumatoid arthritis. Your doctor may also order tests to measure blood levels of other antibodies, including antinuclear antibodies, antibodies to DNA, and antibodies to phospholipids.

What do my test results mean?

Many things may affect your lab test results. These include the method each lab uses to do the test. Even if your test results are different from the normal value, you may not have a problem. To learn what the results mean for you, talk with your health care provider.

A normal test is negative for cryoglobulins. This means the antibodies in your blood stay dissolved even when the blood is chilled.

If you test positive for cryoglobulins, it means these proteins became visibly sludge-like when your blood sample was refrigerated. If your cryoglobulin test is positive, your health care provider will do more tests to find out the cause.

How is this test done?

The test requires a blood sample, which is drawn through a needle from a vein in your arm.

Does this test pose any risks?

Taking a blood sample with a needle carries risks that include bleeding, infection, bruising, or feeling dizzy. When the needle pricks your arm, you may feel a slight stinging sensation or pain. Afterward, the site may be slightly sore.

What might affect my test results?

Other factors aren't likely to affect your results.

How do I get ready for this test?

You may need to not eat or drink anything but water for eight hours before the test.

 

 
Related Items
Wellness Library
  Nutrition to Help Ease Rheumatoid Arthritis
  Essential Self-Care for Arthritis
  Managing Rheumatoid Arthritis
  Taking Care of Arthritis Flares
  Rheumatoid Arthritis: A Range of Treatment
Content Type 167
  CCP
  Rheumatoid Factor (Blood)
Nutritional Supplement Advisor
  Alfalfa
  Borage Oil
  Elderberry
  Histidine
  Manganese
  Nettle
Drug Reference
  Diclofenac; Misoprostol
  Capsaicin
  Flurbiprofen
  Gold Sodium Thiomalate
  Magnesium Salicylate
  Oxaprozin
  Cortisone
  Cyclosporine
  Dexamethasone
  Diclofenac
  Diflunisal
  Etanercept
  Infliximab
  Etodolac
  Rofecoxib
  Fenoprofen
  Anakinra
  Choline Salicylate
  Choline Salicylate; Magnesium Salicylate
  Valdecoxib
  Adalimumab
  Lansoprazole; Naproxen
  Hydrocortisone
  Hydroxychloroquine
  Ibuprofen
  Indomethacin
  Ketoprofen
  Abatacept
  Tocilizumab
  Golimumab
  Meclofenamate Sodium
  Mefenamic Acid
  Meclofenamate, Mefenamic Acid
  Methotrexate
  Methylprednisolone
  Minocycline
  Mycophenolate
  Nabumetone
  Naproxen
  Aspirin, ASA
  Penicillamine
  Piroxicam
  Auranofin
  Prednisolone
  Prednisone
  Aurothioglucose
  Azathioprine
  Salsalate
  Sulfasalazine
  Sulindac
  Tolmetin
  Triamcinolone
  Celecoxib
  Leflunomide
Quizzes
  Arthritis Quiz
  Rheumatoid Arthritis Quiz
Daily News Feed
  Rheumatoid Arthritis Increases Potential for Blood Clots, Study Suggests
  Eating Fish May Be Tied to Lower Rheumatoid Arthritis Risk: Study
  Certain Rheumatoid Arthritis Drugs May Also Protect Patients' Hearts, Studies Find
  Treating Rheumatoid Arthritis Early May Cut Damaging Effects
  Arthritis Drug Could Benefit Some Kidney Disease Patients
  10 Percent of U.S. Adults Physically Limited by Arthritis: CDC
  Rheumatoid Arthritis Patients See Big Boost in Quality of Life
  Breast-Feeding Might Reduce Moms' Odds of Rheumatoid Arthritis
  Shoulder Replacement May Help for Severe Rheumatoid Arthritis
  Pain Can Plague Women After Knee Replacement Surgery
  CT Scans Might Help Diagnose Gout in Some Cases
  Rheumatoid Arthritis May Harm Kidneys
  Could a Few Beers a Week Cut a Woman's Rheumatoid Arthritis Risk?
  Hairless Man Now Hairy, Thanks to Arthritis Drug
Adult Diseases and Conditions
  Online Resources - Arthritis and Other Rheumatic Diseases
  Rheumatoid Arthritis
Newsletters
  People with Diabetes Often Have Arthritis, Too
  Shoulder Surgery Can Relieve RA Symptoms