Health Encyclopedia

 

Health Encyclopedia Home



What Are the Stages of Hodgkin Disease?

What Are the Stages of Hodgkin Disease?

By using exams and tests, a doctor can tell the stage of a person's Hodgkin disease. The stage tells the doctor how much and how far the disease has spread. Staging is 1 of the most important factors in deciding what treatment to have for the disease.

The staging system used most often for Hodgkin is the Cotswold's Modification of the Ann Arbor staging system. The stage of a person's lymphoma is indicated by Roman numerals I, II, III, and IV.

The letter B is added if the person has any B symptoms (fever, night sweats, weight loss). If a person does not have these B symptoms, the letter A is added after the Roman numeral. If the Hodgkin disease involves an organ outside the lymphatic system, the letter E is added. If it involves the spleen, the letter S may be added.

The letter X may be added if a person has bulky disease. This means a tumor in the chest is at least one-third as wide as the chest, or a tumor in another area is at least 10 centimeters (about 4 inches) across. This stage of the disease may need more intensive treatment: 

  • Stage I. Stage I means that the Hodgkin disease is only in 1 group of lymph nodes, or it has started in 1 organ and has not moved to another part of the body.

  • Stage II. Stage II means 2 or more groups of lymph nodes show cancer. The groups of lymph nodes must be on the same side of the diaphragm in the body; all disease is in either the upper or lower half of the body. This means that if the lymph nodes in the neck and underarms both show cancer, it is Stage II. However, if the lymph nodes in the groin and neck show cancer, it is not Stage II, because those 2 parts of the body are on different sides of the diaphragm. Cancer that is in 1 group of lymph nodes and extends directly into a nearby organ is also Stage II.

  • Stage III. Stage III means there are 2 or more groups of lymph nodes with Hodgkin disease on different sides of the diaphragm, such as the neck and groin. There might also be spread of the cancer from the lymph nodes to nearby organs.

  • Stage IV. Stage IV means the Hodgkin disease has spread widely through distant organ(s) outside of the lymphatic system. Other lymph nodes in the body may or may not show signs of the cancer. Typical Stage IV disease is when Hodgkin lymphoma is found in the bone marrow or in organs (lung, stomach, liver, bone) away from the involved lymph nodes.

 
Related Items
Drug Reference
  Chlorambucil
  Cyclophosphamide
  Dacarbazine, DTIC
  Doxorubicin
  Lomustine, CCNU
  Mechlorethamine, Nitrogen Mustard
  Methotrexate
  Procarbazine
  Vinblastine
  Vincristine
  Bleomycin
  Carmustine, BCNU
Cancer Source
  What Is Hodgkin Disease?
  Statistics About Hodgkin Disease
  Can I Get Checked for Hodgkin Disease Before I Have Symptoms
  What Are the Symptoms of Hodgkin Disease
  How the Types of Hodgkin Disease Grow
  I’ve Just Been Told I Have Hodgkin Disease
  What to Know About Radiation for Hodgkin Disease
  What to Know About Stem Cell Transplant for Hodgkin Disease
  Do What You Can to Ease Side Effects from Treatment for Hodgkin Disease
  Now! Don't Wait!
  Tests That Help Evaluate Hodgkin Disease
  How Your Doctor Uses a Biopsy to Diagnose Hodgkin Disease
  Can I Survive Hodgkin Disease? What Is My Prognosis?
  Am I at Risk for Hodgkin Disease?
  Types of Treatment for Hodgkin Disease
  What to Know About Treatment for Recurring Hodgkin Disease
  Follow-Up Care for Hodgkin Disease
Cancer FAQs
  Frequently Asked Questions About Hodgkin Disease
Adult Diseases and Conditions
  Hodgkin Disease
Pediatric Diseases and Conditions
  Hodgkin Lymphoma
  Neck Masses